An updated bibliography, provided by Prof. Callum Fraser, reference many of the published works associated with the HM-JACKarc Faecal Immunochemical Testing analyser.
Studies have concluded that if the FIT is negative and clinical assessment and full blood count normal then the risk of underlying significant bowel disease (SBD) is extremely small. Furthermore, patients with f-Hb ≥400 μgHb/g faeces have >50% risk of SBD and should be investigated urgently. Thus, a single f-Hb requested by GPs provides both a reliable prediction of the absence of SBD, and an objective assessment of the need and urgency of further investigation.Strachan, J., Mowat, C., (2021) eJIFCC, Vol. 32, No. 1, pp. 052-060