Overview of the HM-JACKarc System

HM-JACKarc System and Process

Having been involved with the UK Bowel Cancer Screening Programmes since 1998 Alpha Laboratories has many years’ experience in faecal haemoglobin (f-Hb) testing. The Alpha Laboratories solution for FIT stool testing is the HM-JACKarc system from Kyowa Medex.

HM-JACKarc offers fully automated testing on a compact bench top system, excellent sensitivity at the low end and simple, hygienic sample collection for patients.

This simple to use platform is fully automated to provide high throughput, quantitative f-Hb concentration results with a time to first result of just 5.6 minutes. The methodology is spherical turbidimetry, utilising a latex reagent specific for human haemoglobin.  It has a wide dynamic range from 7ng/ml to 400 ng/ml (ng/ml = µg Hb/g faeces), making it ideal for use in clinical settings for both asymptomatic screening and assessment of samples from symptomatic patients.

Quantitative Faecal Immunochemical Tests (FIT) offer significant advantages over traditional guaiac based tests and qualitative FIT methods, both of which have subjective end points with varying cut off levels.

Automated FIT Testing – Easy as 1, 2, 3

The HM-JACKarc is designed for:

  • Easy use by all grades of laboratory personnel
  • High throughput (200 tests/hour) and so can cope with large daily workloads
  • Testing within a wide dynamic range (0-400 µg of Hb/g of faeces) without requiring sample dilution
  • Cut off settings that can be set at multiple levels to differentiate between Symptomatic testing or Screening
  • Sensitive, quantitative result that enables monitoring of patients with low f-Hb levels
  • Results expressed as ng/ml which is an equivalent numerical value in µg of Hb/g of faeces

For further information regarding FIT Testing with the HM-JACKarc, follow the image links below: